This paper proposed a highly sensitive and user-friendly airborne virus detection method using emission light guidance of 3D photonic crystal (PC) cooperated with Qdot(quantum dot)-aptamer beacon. The proposed biosensor with 3D nanoporous structure has various advantages, such as low-cost, easy-to-use, high sensitive detection and low instrument demand. In addition, output signal can be enhanced through emission light guidance with the specific wave length, which can be engineered by changing nanopore size. Due to high signal-to-noise ratio, not only we can achieve high sensitivity (ultra-low limit of detection (LOD) of 138 pg/ml was obtained), but also high selectivity over other biomolecules. Additionally the target virus can be easily visualized and analyzed through with only a low-cost and portable setup about 20,000 won and a commercial iphone 7 camera.