The Discrete Element Method (DEM) algorithm adopts the simplified model for particle-particle interaction, to simulate massive particle flows in various engineering applications including powder technology, food engineering, civil engineering, and more. However, in the special condition like the fluid flow affects largely on the trajectory of a solid particle such as mineral processing, fluidized bed, or bubble column reactor, the analysis for fluid regime is a key parameter which can be calculated by the Computational Fluid Dynamics (CFD). In this research, the numerical analysis based on the CFD-DEM algorithm to simulate the particle sedimentation under a continuous liquid medium was performed. The spherical particles are initially settled at the funnel above a cylindrical liquid (water) pool. The particles are gravitationally settled on the catcher plate located at the bottom of test section. For the validation of the analysis, the experimental results performed with three types of particles (i.e., Al2O3, ZrO2, Stainless steel) with two sizes of 4, and 6 mm were compared. The resulting parameters related to the particle sedimentation characteristics such as the settling time, the particle velocity, and the particle distribution were examined which showed a good agreement.